Understanding Pigmentary Dispersion Glaucoma: Causes, Symptoms, and Treatment Options

Pigmentary dispersion glaucoma is a lesser-known but important type of glaucoma that can affect younger and more active individuals compared to other forms of the disease. Early detection and treatment are key to protecting vision.

What Is Pigmentary Dispersion Glaucoma?

Pigmentary dispersion glaucoma (PDG) develops when pigment granules from the iris (the colored part of the eye) rub off and clog the eye’s drainage system. This pigment buildup blocks fluid outflow, leading to increased intraocular pressure (IOP). Over time, the elevated pressure can damage the optic nerve, resulting in permanent vision loss if not properly managed.

Who Is at Risk?

Unlike primary open-angle glaucoma, which is more common in older adults, pigmentary dispersion syndrome and its progression to glaucoma often occur in:

  • Younger adults (20s–40s)

  • Men more than women

  • People with nearsightedness (myopia)

  • Those with a family history of glaucoma

Activities that involve vigorous movement, such as running or contact sports, may increase pigment release in some individuals.

Signs and Symptoms

Many patients with pigmentary dispersion glaucoma may not notice symptoms until the disease is advanced, which is why routine eye exams are so important. Still, possible warning signs include:

  • Blurred vision after exercise

  • Seeing halos or rainbow-colored rings around lights

  • Eye pain or pressure

  • Gradual loss of peripheral vision

How Is It Diagnosed?

An optometrist or ophthalmologist can diagnose PDG during a comprehensive eye exam. Specialized testing may include:

  • Gonioscopy: Examining the eye’s drainage angle for pigment buildup

  • Optic nerve imaging and visual field testing: Checking for glaucoma-related damage

  • Tonometry: Measuring eye pressure

  • Slit-lamp examination: Identifying pigment deposits on the cornea or lens

Treatment Options

Treatment for pigmentary dispersion glaucoma is tailored to control eye pressure and prevent further optic nerve damage. Options may include:

  • Prescription eye drops to lower intraocular pressure

  • Laser trabeculoplasty to improve fluid drainage

  • Minimally invasive glaucoma surgery (MIGS) or other surgical procedures for advanced cases

  • Lifestyle modifications, such as avoiding high-impact sports if advised by your doctor

Importance of Regular Eye Exams

Because pigmentary dispersion glaucoma can progress without noticeable symptoms, early detection is critical. Comprehensive eye exams allow your eye doctor to monitor pressure, check for pigment buildup, and detect optic nerve changes before vision loss occurs.

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What Is Pigmentary Dispersion Syndrome?

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